frequency of angiographic ectasia in diagnostic coronary angiography at queen Alia heart institute

To determine the frequency of coronary artery ectasia, and to describe its clinical features and association with coronary artery disease, among patients who underwent diagnostic coronary angiography at Queen Alia Heart Institute. This is a descriptive, and a retrospective review study which was conducted at Queen Alia Heart Institute on 5000 adult patients who underwent diagnostic coronary angiography for chest pain suspicious of angina pectoris during the period between 2006 to 2011. The angiograms reports were reviewed for the presence of coronary artery ectasia, and its manifestations were studied from their medical records. A specially designed medical record abstract form was used to record the following data: Gender, type of coronary ectasia [diffuse or localized], affect coronaries and association with Stenotic Coronary Artery Disease. Simple descriptive statistics [frequency, mean, percentage] were used to describe the study variables. The total number of cardiac angiograms studied was 5000 cases. One hundred-forty patients [2.8%] had coronary ectasia. Males constituted the majority [87.1%] of the affected patients. Isolated right coronary artery ectasia was the commonest [36.4%], but isolated left main ectasia was rare [2.1%]. Ectasia involving all the coronary arteries was found in 19.3% of patients. Diffuse coronary ectasia was found in two thirds of the angiograms, and associated coronary artery disease was found in 56.4% of the ectatic coronaries. Coronary Artery Ectasia is a well recognized and uncommon clinical entity. The diffuse type is more common than the localized one. Right coronary artery is more affected than other coronaries. Multivessel ectasia and coronary stenoses were common in our study patients. Recognition of Coronary Artery Ectasia at angiography is essential for proper therapy and appropriate follow-up for secondary prevention of Coronary Artery Disease

[Study of three common mitochondrial mutations in Arab patients with nonsyndromic hearing loss in Khuzestan province, I.R.Iran]

Hearing Impairment [HI] is the most prevalent neurosensory disorder occurs in 1/1000 newborn. The majority of hearing deficiencies are of genetic origin. About%0-2 of the genetic HI cases are due to mutations in mitochondrial genes. In the present study we investigated the frequency of 3 mtDNA A1555G, A3243G and A7445G mutation of 62 patients with nonsyndromic hearing loss in Khuzestan province. In this descriptive study, we investigated the presence of three mitochondrial mutations; A1555G, A3243G and A7445G in 62 Arab subjects with autosomal recessive non syndromic hearing loss in Khuzestan province. DNA was extracted using standard phenol -chloroform method. The screening of the mitochondrial gene mutations was performed by PCR-RFLP procedure.The possible mutations were confirmed by direct sequencing. None of the investigated mutations; A1555G, A3243G and A7445G were detected in this study. However PCR-RFLP revealed two mutations; G3316A, A7445C in 2 deaf subjects studied. This study is shown that mtDNA mutations consist of G3316A and A7445C are responsible for few of ARNSHL in sample studied and none of the A1555G, A3243G and A7445G mutations are responsible for ARNSHL in this population. The data presented here will improve the genetic counseling of hearing impaired patients in Khuzestan province

Optimization of the production of single cell Protein by Trichoderma viride and Mucor heimalis from date waste

Six mold strains were isolated from the waste of date-processing factories. Trichoderma viride and Mucor heimalis were chosen after it was asserted that they were non toxic. The factors affecting their growth were studied to find the highest rate of protein and biomass production. The best conditions for growth of T. viride were in date syrup containing 3% total soluble solid [TSS],PH 3.5 at 25C, whereas the best growth of M. heimalis were in media containing 5%TSS and pH 4at 30 C. The best nitrogen source for T. viride was 0.2% ammonium sulphate while the best nitrogen source for M. heimalis 0.2% inorganic liquid fertilizer NPK. Moreover, the best concentration of whey which resulted in the highest rate of protein and biomass was 15% for T. viride and 5% M. heimalis. The shaking culture was better than stable culture to reproduce T. viride and M. heimalis which gave the highest production of protion and biomass